Source: The Mercury, Friday, March 18, 1994, p.17
Washington RESEARCHERS have identi- fied a second gene implicated in a hereditary form of colon can- cer, spurring hopes of a screen- ing test within a year. Hereditary nonpolyposis col- on cancer also causes ovarian and uterine cancers. "If you catch the cancer early enough, it's curable," said Ken- neth Kinzler, of the Johns Hop- kins Oncology Centre. Those with the defective genes had up to a 90-per-cent chance of developing colon can- cer, Kinzler said. Women have an additional 30- per-cent chance of developing ovarian or uterine cancer. Richard Kolodner, of Har- vard's Dana-Farber Cancer Centre, said the two genes might be implicated in cancers which were not inherited. "In some people with spor- adic cancer [no history of this cancer in their families] their tumour has an alteration in one of these genes," he said. Studies by teams headed by Kolodner and Kinzler were published in the Journals Science and Nature. Reuter
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